1. Health

Discuss in my forum

What Are the Chances of Having Twins With Clomid?

By , About.com Guide

Updated March 20, 2013

About.com Health's Disease and Condition content is reviewed by the Medical Review Board

Fertility drugs increase your risk of having twins, triplets, or more.

Fertility drugs increase your risk of having twins, triplets, or more.

Image (c) Craig Smallish / Getty
Question: What Are the Chances of Having Twins With Clomid?

Wondering if you'll get your own pair of "clomid twins"? From the way the media paints fertility drugs and multiples, it can seem that everyone taking clomid is bound to have twins, but that's not really true. What are the odds for twins when taking this popular fertility drug?

Answer:

Generally speaking, clomid causes twin pregnancies about 10% of the time, with less than 1% of clomid pregnancies leading to triplets or higher order pregnancies. During clinical trials for clomid, about 7% of pregnancies led to twins, about 0.5% of pregnancies led to triplets and 0.3% to quadruplets.

During the clinical trials of the twin pregnancies, 1 in 5 were identical twins, while 80% of the twin pregnancies were fraternal twins (not identical). (Identical twins come from one egg, not two.)

Some women ask their doctors to give them clomid, not because they are having trouble getting pregnant, but just because they want to get pregnant with twins. There are risks that come with multiple pregnancies, though. You should think twice before purposely trying to get pregnant with twins.

While it's impossible to know who will get pregnant with twins while taking clomid, and who won't, there are some factors that may hint to an increased chance of getting pregnant with twins. Using a higher dosage than necessary may increase the risk of having twins. (Ironically, though, using a higher dosage of clomid than necessary may also decrease the chances of pregnancy occurring at all, because higher doses of clomid can create thick cervical mucus.)

Also, women taking clomid who do not have trouble ovulating or getting pregnant, as well as women younger than 25, may have an increased risk of getting pregnant with twins while taking clomid.

More on twins:

More about clomid:

Would you like to receive trying to conceive tips and fertility information every week? Sign up for a free fertility newsletter here.

Sources:

Clomid Drug Information Sheet. Sanofi-Aventis. Accessed October 6, 2008. http://products.sanofi-aventis.us/clomid/clomid.pdf

Complications and Problems Associated With Multiple Births: Fact Sheet. American Society of Reproductive Medicine. Accessed October 6, 2008. http://asrm.org/uploadedFiles/ASRM_Content/Resources/Patient_Resources/Fact_Sheets_and_Info_Booklets/complications_multiplebirths.pdf

Medications for Inducing Ovulation: A Guide for Patients. American Society of Reproductive Medicine. Accessed October 6, 2008. http://asrm.org/uploadedFiles/ASRM_Content/Resources/Patient_Resources/Fact_Sheets_and_Info_Booklets/ovulation_drugs.pdf

©2013 About.com. All rights reserved.

We comply with the HONcode standard
for trustworthy health
information: verify here.