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Clomid Day by Day: What to Expect, What's Happening in Your Body

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Updated May 06, 2014

Written or reviewed by a board-certified physician. See About.com's Medical Review Board.

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Clomid Cycle Days 10 – 21: Monitoring the Growing Follicles
Woman using an ovulation predictor kit.

Your doctor may recommend using an ovulation predictor kit or ovulation monitor so you can accurately time sex for pregnancy.

Photo: Alis Leonte / Shutterstock

Beyond suggesting that you use an ovulation predictor kit so you can time intercourse for your most fertile days, most gynecologists don't closely monitor clomid treatment cycles, but many reproductive endocrinologists do. Fertility doctors monitor clomid cycles for two primary reasons:

  • to keep an eye on how many follicles grow, so they can cancel the cycle if more than two (or more than one) appear
  • to time a trigger shot (explained in the next step) or an IUI - interuterine insemination

Monitoring the cycle usually starts a few days after your last clomid pill is taken and may involve ultrasounds and blood work every few days until you ovulate. The ultrasound technician will measure the growing follicles, and your doctor will decide — based on their growth — when to time a trigger shot (if you're having one), an IUI, or intercourse for the cycle.

If two follicles develop to a mature size, your doctor may or may not advise you to skip the cycle. Two large follicles raise your odds for conceiving twins, but it's not guaranteed. Tell your doctor if it's important to you to avoid conceiving twins, so she can better advise you on what to do.

If three or more follicles mature, your doctor will likely cancel the cycle, meaning you'll be asked not to have sex (to avoid conceiving). And if an IUI or trigger shot was planned, neither will be given in order to avoid a higher multiple pregnancy, which carries serious risks to you and your future babies.

If your cycle is canceled, as frustrating as this can be (and as tempting as it may be to ignore your doc and have sex anyway), you should take your doctor's warnings seriously. It's actually a good sign that your body reacts to clomid so sensitively, and hopefully in the next cycle, your doctor can adjust your treatment so as not to stimulate as many eggs. It's better to wait until next time than end up with a high risk pregnancy.

Click for the next clomid treatment step.

  1. About.com
  2. Health
  3. Fertility
  4. Fertility Treatments: Clomid, Fertility Drugs, IUI, and IVF
  5. Clomid
  6. Clomid Cycle Days 10 – 21: Monitor Growing Follicles

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